medialprefrontalcortex相关论文
Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeC
Methyl-CpG binding protein 2 (MeCP2) is a basic nuclear protein involved in the regulation of gene expression and microR......
αCaMKII overexpression impairs behavioral flexibility and NMDAR-dependent LTD in the medial prefront
Objective The medial prefrontal cortex(mPFC)participates in the behavioral flexibility.As a major downstream molecule in......
Fear can be highly adaptive in promotingsurvival,yet it can also be detrimental when it persists long after a threat has......
A novel mechanism of methylphenidate on regulating excitatory synaptic transmission in layer Ⅵ/Ⅴ pyr
Objective Methylphenidate (MPH),a reuptake inhibitor of dopamine (DA) and norepinephrine (NE),is widely used as a therap......
The present study investigated the modulation by beta-adrenoceptors (beta-AR s) of excitatory synaptic transmission in l......
α2A-adrenoceptors activation enhances excitability of pyramidal neurons in the medial prefrontal cor
Stimulation of α2A-adrenoceptors in the medial prefrontal cortex (mPFC) improves working memory performance.This improv......
The aim of the present study was to investigate the changes in the firing activity of medial prefrontal cortex(mPFC)neur......
Damage to orbitofrontal cortex(OFC)produces an unusual pattern of deficits.Patients have intact cognitive abilities but ......
Exercise enhances stress coping despite increasing corticosterone,likely by upregulating the dopamin
Introduction:Although exercise has been shown to improve stress coping,the underlying neurotransmitter mechanism remains......
Theta synchronization between medial prefrontal cortex and cerebellum correlates with adaptive perfo
Associative learning is thought to require the coordinated activity of disparate brain structures.For example,in order t......
Anterior cingulate cortex substitutes for the impaired retrieval role of prelimbic cortex in trace e
Objective It has been suggested that the anterior cingulate cortex (ACC) and prelimbic cortex (PL) of medial prefrontal ......
Ionotropic glutamate receptors in medial prefrontal cortex and dorsal hippocampus are involved in di
Objective The medial prefrontal cortex (mPFC) and dorsal hippocampus (DHC) play significant roles in stimulant-induced n......
Oxytocin receptor involved in the inhibition of oxytocin on methamphetamine-induced glutamate releas
Objective Recent studies showed that the oxytocin (OT),a neurohypophyseal neuropeptide which affected adaptive central n......
Intracellular mechanisms underlying α2A-adrenergic suppression of prefrontal cortical excitatory syn
Stimulation of α2A-adrenoceptors (ARs) in the prefrontal cortex (PFC) produces a beneficial effect on cognitive functio......
A number of acute or repeated stimuli can induce expression of DeltaFosB(ΔFosB),a transcription factor derived from the......
Background There are many different ways to depict fear circuits,such as lesions,electrical stimulation,retrograde label......
Deactivation of excitatory neurons in the contralateral prelimbic cortex via Cdk5 promotes pain sens
The medial prefrontal cortex(mPFC)is implicated in processing sensory-discriminative and affective pain.Nonetheless,the ......
Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of L type cal
Allopregnanolone is one of the most important neurosteroids in the brain.We studied the effect and mechanism of allopreg......
The medial prefrontal cortex(mPFC)is implicated in processing sensory-discriminative and affective pain.Nonetheless,the ......
Empathy,a basic prosocial behavior,is referred to as an ability to feel,understand and share others emotional state.Empa......
Effects of GinsenosideRgl on cholinergic and amino acid neurotransmitters in Medial Prefrontal Corte
Objective: To study the role of GinsenosideRgl on improving cognitive impairment of neurodegenerative diseases, dual-pro......
Effects of Ginsenoside Rgl on Acetylcholine,Choline,Glutamate and Taurine in Medial Prefrontal Corte
Objective: To study the role of Ginsenoside Rgl on improving cognitive impairment of neurodegenerative diseases,dual-pro......
Effect of KA and NMDA lesion of the medial prefrontal cortex and dorsal hippocampus on the methamphe
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